产品详情
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Product Name
GBA Mouse mAb
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Gene ID
2629
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SwissProt ID
P04062
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Gene Name
GBA
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Alternative Names
Alglucerase; betaGC; GBA1; GCase; GCB; GLUC; Glucosylceramidase; Imiglucerase
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Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
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Research Field
Neuroscience
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Product Categories
Pathological antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
ZN171
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Isotype
IgG2a
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Immunogen
Human recombinant protein fragment of human GBA (NP_000148) produced in E.coli.
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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