产品详情
-
Product Name
SQSTM1/p62 Mouse mAb
-
Gene ID
8878
-
SwissProt ID
Q13501
-
Gene Name
SQSTM1
-
Alternative Names
SQSTM1; ORCA; OSIL; Sequestosome-1; EBIAP; p60; Ubiquitin-binding protein p62
-
Background
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
-
Research Field
Signal Transduction
-
Product Categories
Pathological antibody
-
Host
Mouse
-
Reactivity
Human
-
Application
IHC-P
-
Dilution Ratio
IHC: 1/50-1/100
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
ZN13
-
Isotype
IgG1
-
Immunogen
Full length human recombinant protein of human SQSTM1 (NP_003891) produced in HEK293T cell.
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。