产品详情
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Product Name
Bid Mouse mAb
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Gene ID
637
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SwissProt ID
P55957
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Gene Name
BID
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Alternative Names
FP497; BID
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Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
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Research Field
Cell Biology
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Product Categories
Pathological antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
ZN139
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Isotype
IgG2b
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Immunogen
Full length human recombinant protein of human BID(NP_001187) produced in HEK293T cell.
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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