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Product Name
Melanocyte Protein PMEL Mouse mAb
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Gene ID
6490
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SwissProt ID
P40967
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Gene Name
PMEL
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Alternative Names
PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV
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Background
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
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Research Field
Tags & Cell Markers
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Product Categories
Pathological antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/100-1/500
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
6G4-6F1-2H10
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Isotype
IgG2b
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Immunogen
Synthesized peptide derived from human PMEL
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.