产品详情
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Product Name
Claudin 18.2 Rabbit mAb
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Gene ID
51208
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SwissProt ID
P56856-2
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Gene Name
Claudin18.2
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Alternative Names
A2;CLDN18.2
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Background
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity).
Required for lung alveolarization and maintenance of the paracellular alveolar epithelial barrier (By similarity).
Acts as a negative regulator of RANKL-induced osteoclast differentiation, potentially via relocation of TJP2/ZO-2 away from the nucleus, subsequently involved in bone resorption in response to calcium deficiency (By similarity).
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Research Field
Signal Transduction
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Product Categories
Pathological antibody
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Host
Rabbit
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/100-1/200
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
R06-1O2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Claudin 18.2.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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