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Product Name
[KD] Caspase 8 Rabbit mAb
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Gene ID
841
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SwissProt ID
Q14790
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Gene Name
CASP8
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Alternative Names
CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
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Background
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.
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Research Field
Cell Biology
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Product Categories
KO/KD validated
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Host
Rabbit
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Reactivity
Human,Hamster
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 55 kDa; Observed MW: 55 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-0D7
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Isotype
IgG
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Immunogen
A synthetic peptide of human Caspase-8
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.