-
Product Name
NTB-A Rabbit mAb
-
Gene ID
114836
-
SwissProt ID
Q96DU3
-
Gene Name
SLAMF6
-
Alternative Names
NTB-A; SLAMF6; Ly108; NK-T-B-antigen; CD352; KALI
-
Background
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
-
Research Field
Immunology
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
FC,ELISA
-
Dilution Ratio
FC: 1/50-1/100 ELISA: 1/10000
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
R04-2U-8
-
Isotype
IgG
-
Immunogen
Recombinant human NTB-A protein
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Lyophilized
-
Buffer System
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
Storage
Store at -20°C to -80°C for 12 months in lyophilized form.