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Product Name
PDPK1 Rabbit mAb
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Gene ID
5170
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SwissProt ID
O15530
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Gene Name
PDPK1
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Alternative Names
PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1
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Background
Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 63 kDa; Observed MW: 63 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-9F7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human PDPK1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.