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Product Name
Paxillin Rabbit mAb
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Gene ID
5829
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SwissProt ID
P49023
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Gene Name
PXN
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Alternative Names
PXN; Paxillin
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Background
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Rat,Hamster
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
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Molecular Weight
Calculated MW: 65 kDa; Observed MW: 65 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-1B4
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Isotype
IgG
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Immunogen
A synthetic peptide of human Paxillin
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.