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Product Name
HDAC8 Rabbit mAb
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Gene ID
55869
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SwissProt ID
Q9BY41
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Gene Name
HDAC8
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Alternative Names
HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8
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Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,ICC/IF,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 42 kDa; Observed MW: 42 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-2B7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human HDAC8
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.