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Product Name
PHOX2B Rabbit mAb
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Gene ID
8929
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SwissProt ID
Q99453
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Gene Name
PHOX2B
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Alternative Names
NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B
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Background
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
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Research Field
Neuroscience
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 32 kDa; Observed MW: 35 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-5G9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human PHOX2B
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.