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Product Name
NRG3 Rabbit mAb
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Gene ID
10718
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SwissProt ID
P56975
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Gene Name
NRG3
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Alternative Names
NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3
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Background
Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
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Research Field
Neuroscience
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 78 kDa; Observed MW: 55 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-9E5
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Isotype
IgG
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Immunogen
A synthetic peptide of human NRG3
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.