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Product Name
SV40 T Antigen Rabbit mAb
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Gene ID
29031019
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SwissProt ID
P03070
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Gene Name
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Alternative Names
Large T antigen; LT; LT-AG
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Background
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.
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Research Field
Infectious Diseases
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
All
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Application
WB,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 82 kDa; Observed MW: 90 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-7D4
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Isotype
IgG
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Immunogen
A synthetic peptide of SV40 T-antigen
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.