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Product Name
Phospho-Paxillin (Tyr118) Rabbit mAb
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Gene ID
5829
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SwissProt ID
P49023
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Gene Name
PXN
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Alternative Names
PXN; Paxillin
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Background
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 65 kDa; Observed MW: 68 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-1V5
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Paxillin
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.