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Product Name
PCPTP1 Rabbit mAb
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Gene ID
5801
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SwissProt ID
Q15256
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Gene Name
PTPRR
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Alternative Names
PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7
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Background
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus .
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 74 kDa; Observed MW: 74 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-8G2
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Isotype
IgG
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Immunogen
A synthetic peptide of human PCPTP1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.