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Product Name
GSDMD Rabbit mAb
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Gene ID
79792
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SwissProt ID
P57764
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Gene Name
GSDMD
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Alternative Names
GSDMD,DFNA5L ,GSDMDC1,FKSG10,Gasdermin-D,Gasdermin domain-containing protein 1
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Background
Gasdermin-D，Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216).
This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed:26375003, PubMed:26375259, PubMed:27281216).
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Research Field
Cell Biology
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Cited
WB (Mouse); IF (Mouse)
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 53 kDa; Observed MW: 53 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-5C5
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Isotype
IgG
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Immunogen
Recombinant protein of human GSDMD
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.