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Product Name
RNF8 Rabbit mAb
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Gene ID
9025
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SwissProt ID
O76064
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Gene Name
RNF8
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Alternative Names
C3HC4 type zinc finger protein; RNF8
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Background
Mediates the ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBE2N/UBC13.
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Research Field
Cell Biology
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 56 kDa; Observed MW: 60 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-6O7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human RNF8
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.