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Product Name
Nrf2 Rabbit mAb
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Gene ID
4780
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SwissProt ID
Q16236
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Gene Name
NFE2L2
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Alternative Names
NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2
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Background
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ICC/IF,IP,ChIP
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Cited
WB (Fish,Rat,Duck,Pig,Catfish); IHC-P (Rat)
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 ChIP: 1/20
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Molecular Weight
Calculated MW: 68 kDa; Observed MW: 100 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-6H3
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Nrf2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.