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Product Name
LIM Kinase 1 Rabbit mAb
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Gene ID
3984
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SwissProt ID
P53667
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Gene Name
LIMK1
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Alternative Names
LIMK1; LIMK; LIM domain kinase 1; LIMK-1
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Background
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
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Research Field
Neuroscience
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 73 kDa; Observed MW: 73 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-7J4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human LIM Kinase 1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.