-
Product Name
EMAP II Rabbit mAb
-
Gene ID
9255
-
SwissProt ID
Q12904
-
Gene Name
AIMP1
-
Alternative Names
p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1
-
Background
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
-
Research Field
Cell Biology
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human,Rat
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 34 kDa; Observed MW: 34 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R01-5A9
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human EMAP II
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.