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Product Name
NOXA Rabbit mAb
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Gene ID
5366
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SwissProt ID
Q13794
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Gene Name
PMAIP1
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Alternative Names
APR; ATL-derived; NOXA; Pmaip1; Protein Noxa
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Background
Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
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Research Field
Cell Biology
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 6 kDa; Observed MW: 10 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-3H6
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Isotype
IgG
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Immunogen
A synthetic peptide of human Noxa
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.