-
Product Name
HDAC2 Rabbit mAb
-
Gene ID
3066
-
SwissProt ID
Q92769
-
Gene Name
HDAC2
-
Alternative Names
HDAC2; Histone deacetylase 2; HD2
-
Background
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
IHC-P
-
Dilution Ratio
IHC: 1/100-1/200
-
Clonality
Monoclonal Antibody
-
Clonality No.
R03-2G-4
-
Isotype
IgG
-
Immunogen
Recombinant protein of human HDAC2
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.