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Product Name
Cubilin Rabbit mAb
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Gene ID
8029
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SwissProt ID
O60494
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Gene Name
CUBN
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Alternative Names
Cubilin; Cubn; IFCR; MGA1; Cubilin precursor; megaloblastic anemia 1
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Background
Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac.
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 399 kDa; Observed MW: 399 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-5I6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Cubilin
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.