-
Product Name
TN-X Rabbit mAb
-
Gene ID
7148
-
SwissProt ID
P22105
-
Gene Name
TNXB
-
Alternative Names
Tenascin X;TNXB;XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; Tenascin-X
-
Background
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
-
Research Field
Signal Transduction
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
IHC-P
-
Dilution Ratio
IHC: 1/100-1/200
-
Clonality
Monoclonal Antibody
-
Clonality No.
R09-2C-2
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human TNXB
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.