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Product Name
TriMethyl-Histone H3 (Lys9) Rabbit mAb
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Gene ID
8350
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SwissProt ID
P68431
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Gene Name
H3-4
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Alternative Names
H3K9me3; H3 histone; HIST1H3A; Histone cluster 1; H3a
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human, Mouse, Rat
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Application
WB,IHC-F,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW:15 kDa;Observed MW: 17 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-4E-9
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Isotype
IgG
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Immunogen
Peptide
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
TriMethylated
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.