-
Product Name
Cleaved N-terminal GSDMD Rabbit mAb
-
Gene ID
79792
-
SwissProt ID
P57764
-
Gene Name
GSDMD
-
Alternative Names
Gasdermin-D, N-terminal;GSDMD-NT;hGSDMD-NTD
-
Background
Gasdermin-D, N-terminal
Promotes pyroptosis in response to microbial infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27418190, PubMed:28392147, PubMed:32820063, PubMed:34289345).
Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1, CASP4 or CASP5 in response to canonical, as well as non-canonical (such as cytosolic LPS) inflammasome activators (PubMed:26375003, PubMed:26375259, PubMed:27418190).
-
Research Field
Cell Biology
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 31 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R07-2C4
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human Cleaved N-terminal GSDMD
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.