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Product Name
Cleaved C-terminal GSDMD Rabbit mAb
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Gene ID
69146
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SwissProt ID
Q9D8T2
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Gene Name
GSDMD
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Alternative Names
Gasdermin-D, C-terminal;GSDMD-CT
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Background
The full-length protein before cleavage is inactive: intramolecular interactions between N- and C-terminal domains mediate autoinhibition in the absence of activation signal (PubMed:26375003, PubMed:28928145, PubMed:29576317, PubMed:32109412).
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Research Field
Cell Biology
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Mouse
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 22 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-5D3
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Isotype
IgG
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Immunogen
A synthetic peptide of mouse Cleaved C-terminal GSDMD
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.