产品详情
-
Product Name
Rat Anti-Mouse CD279/PD-1 mAb (PerCP/Cy5.5)
-
Gene ID
18566
-
SwissProt ID
Q02242
-
Gene Name
Mouse CD279/PD-1
-
Alternative Names
PD-1; Programmed Death-1
-
Background
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
-
Research Field
-
-
Product Categories
Flowcytometry
-
Host
Rat
-
Reactivity
Mouse
-
Application
FC
-
Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
29F.1A12
-
Isotype
IgG2a
-
Immunogen
A synthesized peptide derived from Mouse CD279/PD-1
-
Purification
Affinity Purified
-
Conjugation
PErCP/Cy5.5
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
-
Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。