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Product Name
Rat Anti-Mouse CD117 mAb (AF647)
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Gene ID
16590
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SwissProt ID
P05532
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Gene Name
Mouse CD117
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Alternative Names
Mast/stem cell growth factor receptor Kit; Kit; SCFR; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; CD117
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Background
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
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Research Field
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Product Categories
Flowcytometry
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Host
Rat
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Reactivity
Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
2B8
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Isotype
IgG2b
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Immunogen
A synthesized peptide derived from Mouse CD117
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Purification
Affinity Purified
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Conjugation
AF647
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.