产品详情
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Product Name
CTCF Rat mAb
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Gene ID
13018
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SwissProt ID
Q61164
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Gene Name
Ctcf
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Alternative Names
CTCF; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog
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Background
Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP.
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Research Field
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Product Categories
Primary antibody
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Host
Rat
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Reactivity
Mouse
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 84 kDa; Observed MW: 84 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
7F1
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Isotype
IgG2a
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Immunogen
Recombinant mouse CTCF
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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