货号： 230046
别名： CHTOP; Friend of PRMT1 protein; Small arginine- and glycine-rich protein; SRAG
应用： WB,IHC-F,IHC-P,ICC/IF,IP
反应种属： Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    CHTOP Rat mAb
  • Gene ID
    66511
  • SwissProt ID
    Q9CY57
  • Gene Name
    Chtop
  • Alternative Names
    CHTOP; Friend of PRMT1 protein; Small arginine- and glycine-rich protein; SRAG
  • Background
    Plays an important role in the ligand-dependent activation of estrogen receptor target genes (By similarity). May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.Required for the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC methylates H4R3 and transactivates genes involved in glioblastomagenesis.
  • Research Field
    -
  • Product Categories
    Primary antibody
  • Host
    Rat
  • Reactivity
    Mouse
  • Application
    WB,IHC-F,IHC-P,ICC/IF,IP
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
  • Molecular Weight
    Calculated MW: 26 kDa; Observed MW: 26 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    7C4
  • Isotype
    IgG2a
  • Immunogen
    The C-terminal fragment of mouse CHTOP
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Liquid in PBS containing 0.09% sodium azide as a preservative.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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