-
Product Name
Mouse Anti-Human CD20 mAb (AF488)
-
Gene ID
931
-
SwissProt ID
P11836
-
Gene Name
MS4A1
-
Alternative Names
MS4A1; CD20; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
-
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
-
Research Field
-
-
Product Categories
Flowcytometry
-
Host
Mouse
-
Reactivity
Human
-
Application
FC
-
Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
BCA/B20
-
Isotype
IgG2a
-
Immunogen
A synthesized peptide derived from Human CD20
-
Purification
Affinity Purified
-
Conjugation
AF488
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
-
Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.