-
Product Name
Rat Anti-Mouse/Human CD44 mAb (AF488)
-
Gene ID
960/12505
-
SwissProt ID
P15379/P16070
-
Gene Name
Mouse/Human CD44
-
Alternative Names
CD44 antigen; CD44; CDw44; Epican; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD44; LHR; MDU2; MDU3; MIC4
-
Background
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
-
Research Field
-
-
Product Categories
Flowcytometry
-
Host
Rat
-
Reactivity
Human,Mouse
-
Application
FC
-
Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
-
Molecular Weight
-
-
Clonality
Monoclonal Antibody
-
Clonality No.
IM7
-
Isotype
IgG2b
-
Immunogen
A synthesized peptide derived from Human CD44
-
Purification
Affinity Purified
-
Conjugation
AF488
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
-
Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.