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Product Name
Armenian Hamster Anti-Mouse CD183/CXCR3 mAb (AF488)
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Gene ID
12766
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SwissProt ID
O88410
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Gene Name
Mouse CD183
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Alternative Names
C-X-C chemokine receptor type 3; Cxcr3; CXC-R3; CXCR-3; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183/CXCR3
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Background
CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
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Research Field
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Product Categories
Flowcytometry
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Host
Armenian Hamster
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Reactivity
Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
CXCR3-173
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Isotype
IgG
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Immunogen
A synthesized peptide derived from Mouse CD183
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Purification
Affinity Purified
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Conjugation
AF488
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.