产品详情
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Product Name
Human Anti-SARS CoV/CoV 2 NP Antibody
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Gene ID
43740575
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SwissProt ID
P0DTC9
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Gene Name
N
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Alternative Names
SARS CoV/CoV 2 NP; NC; Protein N
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Background
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May induce inflammasome responses in cultured cells and mice. Acts by interacting with host NLRP3 to facilitate inflammasome assembly, which induces cytokine release that may play a role in COVID lung injury.
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Research Field
Infectious Diseases
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Product Categories
Primary antibody
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Host
Humanized
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Reactivity
Virus
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Application
WB,ICC/IF,FC,ELISA
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Cited
WB (Human)
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 46 kDa; Observed MW: 46 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
-
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Isotype
IgG
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Immunogen
A synthesized peptide derived from SARS CoV/CoV 2 NP
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M PBS, pH 7.2
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Storage
Store at 4°C for at least 6 months. Avoid freeze/thaw cycles
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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样本种属:
Human
杂 志:
Signal Transduction and Targeted Therapy
应用:
WB
IF:
18.187
样本种属:
Human
杂 志:
JOURNAL OF VIROLOGY
应用:
IF
IF:
5.4
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