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Product Name
Rat Anti-Mouse CD40 mAb (PE/Cy5)
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Gene ID
21939
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SwissProt ID
P27512
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Gene Name
Mouse CD40
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Alternative Names
Tumor necrosis factor receptor superfamily member 5; Cd40; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; Tnfrsf5
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Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
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Research Field
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Product Categories
Flowcytometry
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Host
Rat
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Reactivity
Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
FGK4.5/FGK45
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Isotype
IgG2a
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Immunogen
A synthesized peptide derived from Mouse CD40
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Purification
Affinity Purified
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Conjugation
PE/Cy5
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.