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Product Name
Mouse Anti-Rat CD44H mAb (PE/Cy5)
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Gene ID
25406
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SwissProt ID
P26051
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Gene Name
Rat CD44H
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Alternative Names
Pgp-1; H-CAM; CD44s; CD44H
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Background
CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
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Research Field
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Rat
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
OX-49
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Isotype
IgG2a
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Immunogen
A synthesized peptide derived from Rat CD44H
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Purification
Affinity Purified
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Conjugation
PE/Cy5
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.