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货号： 660108

别名： FRAP, FRAP1, FRAP2, RAFT1, RAPT1

应用： WB

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

mTOR Mouse mAb
Gene ID

2475
SwissProt ID

P42345
Gene Name

MTOR
Alternative Names

FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Background

mTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. When sufficient nutrients are available, mTOR responds to a phosphatidic acid-mediated signal to transmit a positive signal to p70 S6 kinase and participate in the inactivation of the eIF4E inhibitor, 4E-BP1. These events result in the translation of specific mRNA subpopulations. mTOR is phosphorylated at Ser2448 via the PI3 kinase/Akt signaling pathway and autophosphorylated at Ser2481. mTOR plays a key role in cell growth and homeostasis and may be abnormally regulated in tumors.
Research Field

Cell Biology
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human,Mouse,Rat
Application

WB
Dilution Ratio

WB：1/500-1/1000
Molecular Weight

Calculated MW: 289 kDa; Observed MW:289 kDa
Clonality

Monoclonal Antibody
Clonality No.

9E2-B3-V8
Isotype

IgG1/Kappa
Immunogen

Peptide
Purification

Protein A
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS, Glycerol and BSA
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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验证详情

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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