产品详情
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Product Name
ILK Mouse mAb
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Gene ID
3611
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SwissProt ID
Q13418
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Gene Name
ILK
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Alternative Names
ILK1, ILK2
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Background
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB：1/500-1/1000
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Molecular Weight
Calculated MW: 51 kDa; Observed MW:51 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
9Q1-Q9-W1
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Isotype
IgG2A/Kappa
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Immunogen
Peptide
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Purification
Protein G
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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