产品详情
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Product Name
HIP1 Mouse mAb
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Gene ID
3092
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SwissProt ID
O00291
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Gene Name
HIP1
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Alternative Names
Huntingtin-interacting protein 1
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Background
HIP1 plays a role in clathrin-mediated endocytosis and trafficking, which is involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. It regulates presynaptic nerve terminal activity. It can enhance androgen receptor (AR)-mediated transcription and may act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. It can bind 3-phosphoinositides (via ENTH domain). It is required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Mouse
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Application
WB, ICC/IF
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Dilution Ratio
WB：1/500-1/1000，ICC/IF：1/50
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Molecular Weight
Calculated MW: 116 kDa; Observed MW:116 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
1L4-D1-V4
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Isotype
IgG1/kappa
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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