产品详情
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Product Name
Calsequestrin 2 Mouse mAb
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Gene ID
845
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SwissProt ID
O14958
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Gene Name
CASQ2
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Alternative Names
CASQ2
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Background
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca2+ ions. Regulates the release of lumenal Ca2+ via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB：1/500-1/1000 IHC-P：1/50-1/100
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Molecular Weight
Calculated MW: 50 kDa; Observed MW:55 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
6Q1-M8-R7
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Isotype
IgG1/Kappa
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Immunogen
Peptide
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Purification
Protein G
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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