产品详情
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Product Name
GRP94 Mouse mAb
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Gene ID
7184
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SwissProt ID
P14625
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Gene Name
HSP90B1
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Alternative Names
HSP90B1, TRA1
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Background
Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.
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Research Field
Tumor biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB：1/500-1/1000
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Molecular Weight
Calculated MW: 95 kDa; Observed MW:100 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
6F6-W3-U2
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Isotype
IgG1/Kappa
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Immunogen
Peptide
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Purification
Protein G
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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