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Product Name
KDM5C/JARID1C/SmcX Mouse mAb
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Gene ID
8242
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SwissProt ID
P41229
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Gene Name
KDM5C
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Alternative Names
Lysine-specific demethylase 5C, Histone demethylase JARID1C, KDM5C
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Background
SMCX, as named KDM5C, belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell differentiation. KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human,Rat
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Application
WB
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Dilution Ratio
WB：1/500-1/1000
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Molecular Weight
Calculated MW: 176 kDa; Observed MW:176 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
8Y7-L7-H8
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Isotype
IgG2a/kappa
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.