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Product Name
DNA-RNA Hybrid [S9.6] Mouse mAb
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Gene ID
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SwissProt ID
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Gene Name
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Alternative Names
DNA-RNA hybrid; RNA/DNA hybrid
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Background
The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity.They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
All
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Application
ICC/IF,IP,ChIP
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Dilution Ratio
IF: 1/50-1/200 IP: 1/50-1/300 ChIP: 1/20
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
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Isotype
IgG2a
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Immunogen
ΦX174 bacteriophage-derived synthetic DNA/RNA
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.