货号： 660172
别名： Imp4b, RanBP4, IMP4B, RANBP4
应用： WB
反应种属： Human
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    IPO4 Mouse mAb
  • Gene ID
    79711
  • SwissProt ID
    Q8TEX9
  • Gene Name
    IPO4
  • Alternative Names
    Imp4b, RanBP4, IMP4B, RANBP4
  • Background
    Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Mouse
  • Reactivity
    Human
  • Application
    WB
  • Dilution Ratio
    WB：1/500-1/1000
  • Molecular Weight
    Calculated MW: 119 kDa; Observed MW:130 kDa
  • Clonality
    Monoclonal Antibody
  • Clonality No.
    6K5-J9-A5
  • Isotype
    IgG1/Kappa
  • Immunogen
    Peptide
  • Purification
    Protein G
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    Liquid in PBS, Glycerol and BSA
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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