您现在的位置：首页 > 产品中心 > 抗体系列 > 精品一抗

货号： 660183

别名： CRACC, SLAMF7, CS1, FOAP-12

应用： ICC/IF,FC

反应种属： Human

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：3-4个工作日说明书PDF

产品详情

Product Name

CD319 Mouse mAb
Gene ID

57823
SwissProt ID

Q9NQ25
Gene Name

SLAMF7
Alternative Names

CRACC, SLAMF7, CS1, FOAP-12
Background

Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated. Besides, positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K.In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells.
Research Field

Cell Biology
Product Categories

Primary antibody
Host

Mouse
Reactivity

Human
Application

ICC/IF,FC
Dilution Ratio

ICC/IF：1/50，FC：1/50-1/100
Molecular Weight

–
Clonality

Monoclonal Antibody
Clonality No.

8H9-Z3-H8
Isotype

IgG2b/Kappa
Immunogen

Peptide
Purification

Protein G
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

Liquid in PBS, Glycerol and BSA
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

展开更多

验证详情

展开更多

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

引用文献更多完整详情

用户反馈

全部评论( 0)
好评( 0)
中评( 0)
差评( 0)
有图( 0)

推荐排序

最近评价
推荐排序

转到页确认

产品评论

评论内容：

商品评分

E-订阅最新信息

给我们发消息

微信扫码关注

蜀ICP备13012294号-2

川公网安备 51012202001504号

犀牛云提供企业云服务