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Product Name
Mouse Anti-Human/Mouse/Rat CD47 mAb (EV450)
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Gene ID
961/16423/29364
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SwissProt ID
Q08722/Q61735/P97829
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Gene Name
Human/Mouse/Rat CD47
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Alternative Names
Leukocyte surface antigen CD47; Cd47; Integrin-associated protein; IAP
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Background
CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
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Research Field
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Human,Mouse,Rat
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
MIAP410
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Isotype
IgG1
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Immunogen
A synthesized peptide derived from Human CD47
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Purification
Affinity Purified
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Conjugation
EV450
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.