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Product Name
Mouse Anti-Human CD27 mAb (ER780)
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Gene ID
939
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SwissProt ID
P26842
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Gene Name
CD27
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Alternative Names
CD27; CD27L receptor; LPFS2; S152; T14; TNFRSF7; TNFSF7; Tp55
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Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
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Research Field
Immunology
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Human
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
O323
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Isotype
IgG1
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Immunogen
A synthesized peptide derived from Human CD27
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Purification
Affinity Purified
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Conjugation
ER780
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.