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Product Name
Mouse Anti-Mouse IL-17A mAb (FITC)
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Gene ID
16171
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SwissProt ID
Q62386
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Gene Name
Mouse IL-17A
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Alternative Names
Interleukin-17A; Il17a; Ctla11
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Background
The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis.
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Research Field
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Product Categories
Flowcytometry
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Host
Mouse
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Reactivity
Mouse
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Application
FC
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Dilution Ratio
FC: 5μL per test for million cells or whole blood in 100 μL volume.
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Molecular Weight
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Clonality
Monoclonal Antibody
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Clonality No.
17F3
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Isotype
IgG1
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Immunogen
A synthesized peptide derived from Mouse IL-17A
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Purification
Affinity Purified
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Conjugation
FITC
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS with 0.05% Proclin300, 1% BSA
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Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.