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Product Name
CTNNB1(S37F Mutant) Mouse mAb
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SwissProt ID
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Gene Name
Beta-catenin, CTNNB, Catenin beta-1
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Alternative Names
Beta-catenin, CTNNB, Catenin beta-1
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Background
CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that from adherents junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls double duty as an intracellular signal transducer in the Wnt signaling pathway. Mutations of CTNNB1 have been implicated in the pathogenesis of several cancers.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P,ELISA
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Dilution Ratio
ELISA: 1/1000-1/5000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
3S7-A7-N9
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of CTNNB1 which includes the mutation of S37F, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing